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Anders Rosengren Group

Anders Rosengren, MD, Associate Senior Lecturer (Assistant Professor), integrates clinical investigations, bioinformatics and experimental studies and aims to better understand the pathophysiology of type 2 diabetes and to identify more specific treatment targeted at the underlying disease mechanisms.

He is PI for the "Detailed Mapping of Type 2 Diabetes" (DIACT) study, which is a longitudinal patient study that investigates how the major pathophysiological components in type 2 diabetes are interlinked and develop over time. This is combined with global genetic, gene expression and metabolite data to identify biomarkers associated with pathophysiological components.

Network analysis and other bioinformatics approaches are used to integrate genetic and gene expression data from the patients and to identify disease genes. Candidate genes identified from these analyses are studied experimentally to investigate underlying disease mechanisms. Moreover, a method for drug repositioning is used that compares the gene networks that are perturbed in T2D with a large library of gene expression signatures from drugs to identify potential anti-diabetic compounds.

International Collaborations

Anders Rosengren has extensive international collaborations, which includes e.g. Sage Bionetworks in Seattle and University of Oxford. Anders Rosengren was appointed a Ragnar Söderberg researcher in Medicine 2013. He has also recently been awarded a 5-year Future Research Leader grant by the Swedish Foundation for Strategic Research.

Anders Rosengren is also PI for PriusHealth, a study aiming to develop new research-based web tool for patients with type 2 diabetes. This tool will integrate biological and lifestyle aspects of type 2 diabetes and aims to improve patient self-management. The tool is developed in close collaboration with patients in a research study.

Participation

Patients with type 2 diabetes who are interested in participating in the PriusHealth study to develop and test this new treatment tool may contact us via www.forskningsstudie.se.

Page Manager: Pontus Sundén|Last update: 5/12/2017
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Denna text är utskriven från följande webbsida:
http://wcmtm.gu.se/research-groups/rosengren/
Utskriftsdatum: 2017-11-21